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Formula: C25H24N8O7S2
Smiles: COC1=CC=C2C(OC(C)(C)C3=C4C(=CC=C23)C(=O)N(C2C=CC(=CC=2)C(=O)C2C=CC=CC=2)C4=O)=C1O
CAS Number: 1285446-04-9
The caspase 9 inhibitor Z-LEHD-FMK protects human liver cells while permitting death of cancer cells exposed to tumor necrosis factor-related apoptosis-inducing ligand
Fedratinib hydrochloride hydrate ((2S)-1 2-propanediol hydrate) Formula: C25H24N8O7S2Fedratinib hydrochloride hydrate (TG 101348 hydrochloride hydrate) is a potent, selective, ATP competitive and orally active JAK2 inhibitor with IC50s of 3 nM for both JAK2 and JAK2V617F kinase. Fedratinib hydrochloride hydrate shows 35 and 334 fold selectivity over JAK1 and JAK3, respectively. Fedratinib hydrochloride hydrate induces cancer cell apoptosis and has the potential for myeloproliferative disorders research. Product information CAS Number:
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US$ 488.48
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